Written by Brandon Topp

Disclaimer: Mood is not a medical or wellness source. If you're looking to learn more about topics like potential benefits, mental health, or physical pain, please consult a qualified healthcare professional.

Some cannabis strains provide an energetic lift, while others encourage deep physical relaxation and mental clarity.

If you're searching for the best cannabis strains to help you wind down, settle in, and feel at ease, our soothing cannabis strains and products are absolutely worth checking out.

Whether you’re looking to experience calming psychoactive effects, alleviate tension, or enhance your overall well-being, the right strain can make all the difference.

This guide will break down our favorite mental relaxation and full-body calm strains, all featured in Mood’s Soothing Cannabis selection.

Table of Contents

• What Makes a Weed Strain Soothing?

• The Cannabis Sativa vs. Indica Debate

• The Role of Cannabinoids and Terpenes in Relaxing Strains

• The Best Soothing Weed Strains

  • Devil’s Mistress

  • Birthday Cake

  • Oreoz

  • Purple Punch

  • Wedding Cake

  • Peace Potion

• Choosing the Right Soothing Weed Strain

What Makes a Weed Strain Soothing?

Not all cannabis strains produce the same effects. Some strains deliver stimulating effects, while others are known for their soothing effects, supporting mental and deep physical relaxation.

There's also a lot of overlap. A relaxing weed strain can double as a sleepy weed strain or soothing weed strain, and for some, it can be great for productivity, while for others, it is strictly for deep relaxation.

Experience is shaped by strain but also by a user's particular tolerance, taste, and sensibilities.

The best soothing weed strains tend to be indica-dominant strains or 50/50 hybrids with a balanced mix of THC and terpenes that promote relaxation without excessive sedation.

Many cannabis users report that strains with both THC and CBD provide soothing effects like a relaxing body high or heightened sleep quality while maintaining a calm, enjoyable high.

The Cannabis Sativa vs. Indica Debate

Cannabis users often debate the differences between sativa strains and indica dominant strains.

Traditionally, sativa-dominant strains are known for their stimulating effects, while indica-dominant strains are linked to relaxing effects that promote well-being.

However, research shows that a strain’s chemical makeup—including its THC content, cannabinoid profile, and terpene composition—plays a much bigger role in determining its effects than whether it’s labeled sativa or indica.

Many sativa-dominant hybrids contain mood-boosting properties that enhance mental relaxation, while certain indica-dominant strains encourage deep physical relaxation without causing excessive sedation.

For some of the best sativa strains available online, check out more upbeat categories on Mood's website, such as Energized and Focused.

The Role of Cannabinoids and Terpenes in Relaxing Strains

Your serotonin receptors interact with the body's endocannabinoid system when regulating mood, relaxation, and stress relief.

Cannabinoids like THC and CBD bond with endocannabinoid receptors to deliver their effects, which can vary and get more specific based on things like THC levels, terpene content, and the quality of cannabis flower or product.

High levels of THCa, in particular, contribute to the soothing effects of many of the best weed strains for relaxation.

Cannabinoids That Support Relaxation

• THCa (Tetrahydrocannabinolic Acid): Becomes more potent when heated, delivering psychoactive effects that can hit the spot when you're tired at the end of the day and may be looking for some mental relaxation or stress relief.

• CBD (Cannabidiol): Found in some of the best hybrid strains and most cannabis flower, CBD enhances therapeutic effects and helps balance the intensity of THC.

Cannabis Terpenes That Promote Relaxation

Terpenes contribute to the soothing effects of many strains.

The best soothing weed strains often contain the following terpenes:

• Myrcene: Found in Purple Punch and Oreoz, myrcene enhances deep physical relaxation.

• Linalool: Common in Wedding Cake, this floral terpene contributes to calming properties.

• Caryophyllene: Present in Birthday Cake, this spicy terpene works with THC to produce relaxing effects.

The Best Soothing Weed Strains

Mood’s Soothing selection features high-quality cannabis strains designed for deep physical and mental relaxation and an overall sense of well-being.

Devil’s Mistress – The Ultimate Wind-Down

For those seeking full-body relaxation, Devil’s Mistress is an indica-dominant hybrid with soothing effects that settle into both the mind and body.

This strain is perfect for times when you're looking to kick back after a long day.

• Type: Indica-dominant Hybrid

• Effects: Relaxing, full-body calm, soothing

• Flavor Profile: Earthy, warm chocolate with spicy herbs

Pick up a gram of Devil's Mistress THCa Flower from Mood for $17 today.

Birthday Cake – The Cozy Indulgence

Birthday Cake is a balanced hybrid known for its mood-boosting properties and soothing effects.

This strain provides a delightful sensory experience, perfect for unwinding without heavy sedation.

• Type: 50/50 hybrid

• Effects: Comforting, mellow, lightly euphoric

• Flavor Profile: Caramelized sugar, earthy vanilla, sweet almond

Treat yourself to an eighth of Birthday Cake Flower from Mood if this sounds like the strain for you.

Oreoz – The Heavy Hitter

For a high-THC cannabis strain that promotes deep physical relaxation, Oreoz is the go-to.

This potent hybrid delivers a slow-building, full-body calm that’s perfect for nighttime use.

• Type: Indica

• Effects: Heavy, deeply calming, couch-lock

• Flavor Profile: S'mores, spicy herbs, chocolate

Splurge and stock up with a quarter of Oreoz Flower for only $93 at Mood's online shop.

Purple Punch – The Body High Champion

Purple Punch is one of the best indica strains for relaxing effects and soothing body highs.

It’s an excellent choice for winding down and promoting well-being after a long day.

• Type: Indica-dominant hybrid

• Effects: Full-body relaxation, peaceful, mood-boosting

• Flavor Profile: Grape candy, berry punch, and muffins

A full ounce of Purple Punch THCa Flower is available for only $255 at the Mood Shop.

Wedding Cake – The Balanced Soother

A favorite among the best hybrid strains, Wedding Cake delivers a soothing body high while keeping the mind clear and at ease.

It’s perfect for those who want to relax without feeling sluggish.

• Type: Indica-dominant Hybrid

• Effects: Relaxing, euphoric, physically soothing

• Flavor Profile: Eathy nuttiness, caramelized sugar, vanilla

Order yourself a Wedding Cake Pre-Roll for only $16 at Mood's online shop today.

Peace Potion – The Tranquility Blend

Peace Potion is a perfect choice for an even hybrid that provides soothing effects without sedation.

It balances mental relaxation with a gentle body high, making it an excellent option for unwinding without feeling too heavy.

• Type: Hybrid

• Effects: Balanced, peaceful, lightly euphoric

• Flavor Profile: Lavender, moss, and citrus

Order a 5-pack of Peace Potion THCa Pre-Rolls for $64.

Choosing the Right Soothing Weed Strain

The best soothing weed strain depends on your preference.

If you’re looking for deep physical relaxation, Oreoz and Purple Punch are excellent choices.

Wedding Cake and Peace Potion are great options if you want a balanced hybrid with mood-boosting properties.

For a heavier buzz, seek out potent THC content, and for something more middle of the road, zero in on moderate THC levels or THCa levels.

For the body effects many of us love when seeking a soothing cannabis option, definitely prioritize indica-dominant options over sativa-dominant ones.

Shop Soothing Weed Strains at Mood

At Mood, we offer high-quality cannabis strains designed to promote well-being, relaxation, and peace of mind.

Whether you prefer an indica-dominant strain or a sativa-dominant hybrid, we have the perfect strain.

Explore our full selection of Soothing strains and discover your ideal way to relax.